Rizatriptan is referred to as a triptan or selective serotonin receptor agonist, prescribed for acute migraine attacks. Its central mechanism and the one for which it is used today (mainly) is to constrict arteries around the brain and reduce release of neuropeptides that generate many symptoms during a migraine. There are downsides, however: as with all medications rizatriptan can cause side effects and these sometimes matters quite seriously.
Dizziness is one of the most common side effects, and clinical trials published in The Journal of Headache and Pain report that as many as 14% (809 out of 5804 patients) reported dizziness. For those who have migraines with visual aura, this could be the cause for loss of balance to begin within attack itself. Somnolence is also seen in 10% of patients and can limit daily activities, especially if multiple doses are required over a 24-hour period.
Rizatriptan is a vasoactive drug, and so there are also concerns regarding cardiovascular side effects. In 6-9% of patients, (mainly in those with cardiovascular disease), episodes of palpitations experience chest tightness and heart quickening happening. This is a more common risk in the elderly, which can cause healthcare providers to be more cautious when rizatriptan determining oral-contraceptive.nu/,ki.,rx / prescribing treatments by persons aged over 65 years of age old(pool.head()). But a 2006 publication by the American College of Cardiology also highlighted that patients should be screened for existing heart conditions before starting triptan therapy, as it could exacerbate underlying diseases.
Tingling or numbness are also commonly reported side effects, which affect about 7% of users. This adverse effect often occurs in the extremities and is sometimes confused with a sign of another severe neurological problem. Healthcare providers typically try to empathize with men who convey this, and assure them is usually benign if not just slightly disconcerting.
Common side effects with rizatriptan are (occurring in more than 1 percent of people):Digestive: Nausea, dry mouth*///<11-15%> These effects are likely dose-dependent, more manifest at the 10 mg dosage compared to 5 mg. In this case, the side effects may be able to managed by increasing or timing the medication correctly.
Serotonin syndrome, a serious but rare side effect that can be life-threatening This risk is important to consider when taking rizatriptan in addition with other serotonergic drugs such as SSRIs or SNRIs, which are prescribed for depression and anxiety. Serotonin Syndrome: Symptoms include rapid heart rate, agitation and muscle stiffness. Doctors stress that these signs should set off the alarm and they demand urgent attention.
The problem is headache recurrence: typically 20-30% of users will have their migraine return within a day. The overuse of triptans is a well-known limitation, which can result in patients using the medication too frequently and therefore be at higher risk for worse side effects. This issue can be mitigated by establishing correct dosing schedules and becoming familiar with adjunct therapies.
It is important for patients that are at the risk of rizatriptan side effects to be informed about both common and serious risks related with this medication. Lastly, it is important to consult with a healthcare provider before beginning treatment rizatriptan; This also applies if there are pre-existing conditions or additional medications involved, in order o maximize the beneficial effects of triptans and minimize the potential disadvantages.